The Dallas Cowboys will be on the road for the first time this season when they travel to MetLife Stadium to take on the New York Giants on Monday Night Football.

The Cowboys split their two home games to start the 2022 NFL season, losing 19-3 to the Tampa Bay Buccaneers before beating the Bengals 20-17 in Sunday's final game. 

Quarterback Dak Prescott was injured in the loss to Tampa Bay and is out after surgery, but Cooper Rush did well to get the win over Carolina. The Giants are 2-0 for the first time since 2016 and bring confidence to the NFC East showdown. 

They started the season with a 21-20 win over Tennessee, the AFC's top seed in the finals. They followed that up with a 19-13 win over Carolina on Sunday, and new coach Brian Daboll seemed to put the fight on a team that went 4-13 in 2021. 

The race was set to begin at 8:15 p.m. ET at MetLife Stadium in East Rutherford, New Jersey. Caesars Sportsbook favors New York as a 1-point favorite in the latest Cowboys vs. Giants odds 

the over/under for the total run is 39.5. Before locking up any Giants vs. Cowboys picks and you want to check out NFL predictions and SportsLine's preview betting tips. 

the over/under for the total run is 39.5. Before locking up any Giants vs. Cowboys picks and you want to check out NFL predictions and SportsLine's preview betting tips. 

The model, which simulates every NFL game 10,000 times, has grown to more than $7,000 for players and $100 over NFL picks since its inception.